- Soc Sci Med. 1988;27(12):1381-6 - PubMed
- Clin Pharmacol Ther. 2019 Dec;106(6):1236-1245 - PubMed
- Int J Antimicrob Agents. 2019 Sep;54(3):375-379 - PubMed
- Br J Clin Pharmacol. 2017 Aug;83(8):1860-1861 - PubMed
- Med Teach. 2016 Apr;38(4):425 - PubMed
Introduction: Twenty-five years ago, the World Health Organization (WHO) published the Guide to Good Prescribing (GGP), followed by the accompanying Teacher's Guide to Good Prescribing (TGGP). The GGP is based on a normative 6-step model for therapeutic reasoning and prescribing, and provides a six-step guide for students to the process of rational prescribing.
Method: We reviewed the need to update both WHO publications by evaluating their use and impact, including new (theoretical) insights and demands. Based on information from literature, Internet, and other (personal) sources, we draw the following conclusions.
Results: 1. An update of the GGP and TGGP, both in terms of content and form, is necessary because of the current need for these tools (irrational medicine use and unavailability of medicines), the lack of similar documents, and the lack of connection with recent developments, such as Internet and modern education; 2. The basic (6-step) model of the GGP is effective in terms of rational prescribing in the undergraduate situation and is still consistent with current theories about (context) learning, clinical decision-making, and clinical practice; 3. The dissemination and introduction of the GGP and TGGP in education has been successful so far, but is still not optimal because of lack of support and cooperation.
Conclusions: On the basis of the evaluation results, a plan for the revision of the GGP and TGGP is presented.
Keywords: Clinical pharmacology; Education; Guide to good prescribing; Pharmacotherapy; Rational prescribing; WHO 6 step.
Hassan NA, Abdulla AA, Bakathir HA, Al-Amoodi AA, Aklan AM, de Vries TP. Hassan NA, et al. Eur J Clin Pharmacol. 2000 Feb-Mar;55(11-12):873-6. doi: 10.1007/s002280050710. Eur J Clin Pharmacol. 2000. PMID: 10805067 Clinical Trial.
Richir MC, Tichelaar J, Stanm F, Thijs A, Danner SA, Schneider AJ, de Vries TP. Richir MC, et al. Clin Pharmacol Ther. 2008 Oct;84(4):513-6. doi: 10.1038/clpt.2008.82. Clin Pharmacol Ther. 2008. PMID: 19238657
Akici A, Gören MZ, Aypak C, Terzioğlu B, Oktay S. Akici A, et al. Eur J Clin Pharmacol. 2005 Oct;61(9):643-50. doi: 10.1007/s00228-005-0960-3. Epub 2005 Oct 19. Eur J Clin Pharmacol. 2005. PMID: 16187133
Hogerzeil HV. Hogerzeil HV. Br J Clin Pharmacol. 1995 Jan;39(1):1-6. doi: 10.1111/j.1365-2125.1995.tb04402.x. Br J Clin Pharmacol. 1995. PMID: 7756093 Free PMC article. Review.
Gwee MC. Gwee MC. Med Teach. 2009 Sep;31(9):847-54. doi: 10.1080/01421590903168119. Med Teach. 2009. PMID: 19811191 Review.
Kıyak YS, Coşkun Ö, Budakoğlu Iİ, Uluoğlu C. Kıyak YS, et al. Eur J Clin Pharmacol. 2024 May;80(5):729-735. doi: 10.1007/s00228-024-03649-x. Epub 2024 Feb 14. Eur J Clin Pharmacol. 2024. PMID: 38353690
Mokrzecki SM, Mallett A, Sen Gupta T, Perks S, Pain T. Mokrzecki SM, et al. Med Educ Online. 2023 Dec;28(1):2259166. doi: 10.1080/10872981.2023.2259166. Epub 2023 Sep 18. Med Educ Online. 2023. PMID: 37722675 Free PMC article. Review.
Budakoğlu Iİ, Coşkun Ö, Kıyak YS, Uluoğlu C. Budakoğlu Iİ, et al. Eur J Clin Pharmacol. 2023 Mar;79(3):341-348. doi: 10.1007/s00228-022-03448-2. Epub 2023 Jan 9. Eur J Clin Pharmacol. 2023. PMID: 36622428 Review.
Sultan R, van den Beukel TO, Reumerman MO, Daelmans HEM, Springer H, Grijmans E, Muller M, Richir MC, van Agtmael MA, Tichelaar J. Sultan R, et al. Clin Pharmacol Ther. 2022 Apr;111(4):931-938. doi: 10.1002/cpt.2475. Epub 2021 Nov 17. Clin Pharmacol Ther. 2022. PMID: 34729774 Free PMC article. Clinical Trial.
Mokrzecki S, Pain T, Mallett A, Perks S. Mokrzecki S, et al. Front Med (Lausanne). 2021 Sep 23;8:732054. doi: 10.3389/fmed.2021.732054. eCollection 2021. Front Med (Lausanne). 2021. PMID: 34631750 Free PMC article.